{"id":17926,"date":"2024-10-07T23:31:42","date_gmt":"2024-10-07T16:31:42","guid":{"rendered":"https:\/\/dcl.com.vn\/cproduct\/mobium\/"},"modified":"2026-02-11T13:58:47","modified_gmt":"2026-02-11T06:58:47","slug":"mobium","status":"publish","type":"cproduct","link":"https:\/\/dcl.com.vn\/en\/cproduct\/mobium\/","title":{"rendered":"MOBIUM\u00ae"},"content":{"rendered":"\n<p><span style=\"font-size: 14pt;\"><strong>Dosage &amp; Administration<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"font-size: 14pt;\"><strong>Administration<\/strong>: Use the lowest effective dose for the shortest duration to control nausea and vomiting. Should be taken before meals. If taken after a meal, absorption may be delayed. Patients should take the medication at a fixed time. If a dose is missed, skip it and continue with the regular schedule. Do not double the dose to compensate for a missed one. The maximum treatment duration should not exceed one week.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\"><strong>Dosage<\/strong>:<\/span>\n<ul>\n<li><span style=\"font-size: 14pt;\"><strong>Adults and adolescents (12 years or older and weighing \u2265 35kg)<\/strong>: 1 tablet per dose, up to 3 times daily, with a maximum dose of 30 mg\/day.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\"><strong>Children under 12 years and adolescents under 35kg<\/strong>: This formulation is not recommended.<\/span><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-size: 14pt;\"><strong>Special Populations<\/strong>:<\/span>\n<ul>\n<li><span style=\"font-size: 14pt;\"><strong>Hepatic Impairment<\/strong>: Contraindicated in patients with moderate to severe hepatic impairment. No dose adjustment is needed for mild hepatic impairment.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\"><strong>Renal Impairment<\/strong>: Due to the prolonged half-life of domperidone in severe renal impairment, a lower dose or extended dosing interval should be used depending on the severity of the condition. These patients require close monitoring during long-term treatment.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><span style=\"font-size: 14pt;\"><strong>Contraindications<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"font-size: 14pt;\">Hypersensitivity to domperidone or any component of the medication.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\">Patients with moderate to severe hepatic impairment.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\">Patients with prolonged cardiac impulse conduction time, especially the QT interval, significant electrolyte disturbances, or pre-existing cardiac conditions such as congestive heart failure.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\">Concomitant use with QT-prolonging drugs.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\">Concomitant use with strong CYP3A4 inhibitors (regardless of QT-prolonging effect).<\/span><\/li>\n<li><span style=\"font-size: 14pt;\">Concomitant use with neurokinin-1 receptor antagonist antiemetics in the brain.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\">Gastrointestinal hemorrhage or perforation.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\">Mechanical intestinal obstruction.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\">Prolactin-secreting pituitary tumor (prolactinoma).<\/span><\/li>\n<\/ul>\n<p><span style=\"font-size: 14pt;\"><strong>Storage &amp; Quality<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"font-size: 14pt;\"><strong>Storage<\/strong>: Store in a cool, dry place at a temperature below 30\u00b0C, away from light.<\/span><\/li>\n<li><span style=\"font-size: 14pt;\"><strong>Shelf Life<\/strong>: 36 months from the manufacturing date.<\/span><\/li>\n<li><strong style=\"font-size: 14pt;\">Quality Standard<\/strong><span style=\"font-size: 14pt;\">: Manufacturer&#8217;s Standard.<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Symptomatic treatment of nausea and vomiting<\/p>\n","protected":false},"featured_media":14186,"template":"","product-category":[186],"factory-product-category":[182],"class_list":["post-17926","cproduct","type-cproduct","status-publish","has-post-thumbnail","hentry","product-category-nhom-tieu-hoa-en","factory-product-category-pharmaceutical-factory"],"acf":[],"_links":{"self":[{"href":"https:\/\/dcl.com.vn\/en\/wp-json\/wp\/v2\/cproduct\/17926"}],"collection":[{"href":"https:\/\/dcl.com.vn\/en\/wp-json\/wp\/v2\/cproduct"}],"about":[{"href":"https:\/\/dcl.com.vn\/en\/wp-json\/wp\/v2\/types\/cproduct"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dcl.com.vn\/en\/wp-json\/wp\/v2\/media\/14186"}],"wp:attachment":[{"href":"https:\/\/dcl.com.vn\/en\/wp-json\/wp\/v2\/media?parent=17926"}],"wp:term":[{"taxonomy":"product-category","embeddable":true,"href":"https:\/\/dcl.com.vn\/en\/wp-json\/wp\/v2\/product-category?post=17926"},{"taxonomy":"factory-product-category","embeddable":true,"href":"https:\/\/dcl.com.vn\/en\/wp-json\/wp\/v2\/factory-product-category?post=17926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}