Indications
- Adults:
- Treatment of cortical myoclonus: Nootripam is used for the treatment of cortical myoclonus of any etiology and should be used in combination with other anti-myoclonic therapies.
- Symptomatic treatment of psycho-organic syndrome: Treats symptoms of psycho-organic syndrome where improvement is expected from treatment, such as memory impairment, poor concentration, lack of alertness, mood changes, behavioral disorders, inattention to self, and senile dementia due to multiple cerebral infarcts.
- Treatment of vertigo: Treats vertigo and related balance disorders, except for dizziness of vasomotor or psychological origin.
- Prevention and reduction of vaso-occlusive crises in sickle cell anemia.
- Children:
- Treatment of dyslexia: In combination with appropriate measures such as speech therapy.
- Prevention and reduction of vaso-occlusive crises in sickle cell anemia.
Dosage & Administration
- Administration: Oral use. Can be taken with or without food. Swallow the tablet whole with water.
- Dosage:
- Adults:
- Cortical myoclonus: The daily dose should start at 7.2 g, divided into 2-3 doses (equivalent to 2400 mg/dose, 3 times daily). Depending on the response, increase by 4.8 g/day (4800 mg/day) every 3-4 days, up to a maximum dose of 24 g/day (24000 mg/day). Treatment with other anti-myoclonic drugs should be maintained at the same dosage. If clinical benefits are achieved, the dose of other drugs can be reduced.
- Symptomatic treatment of psycho-organic syndrome: The recommended daily dose is 2.4 g – 4.8 g (2400 mg – 4800 mg), divided into 2-3 doses (equivalent to 800 mg – 1600 mg/dose, 3 times daily).
- Vertigo: The recommended daily dose is 2.4 g – 4.8 g (2400 mg – 4800 mg), divided into 2-3 doses (equivalent to 800 mg – 1600 mg/dose, 3 times daily).
- Sickle cell anemia:
- For prevention: The recommended daily dose is 160 mg/kg of body weight, divided into 4 doses.
- For relief of acute crises: The recommended daily dose is 300 mg/kg of body weight, administered intravenously, divided into 4 doses.
- Children:
- Dyslexia: The recommended dose for children ≥ 8 years is 3.2 g/day (3200 mg/day or 8 tablets/day), divided into 2-3 doses, taken regularly throughout the school year.
- Sickle cell anemia: For children 3 years and older, the dose for crisis prevention is 160 mg/kg of body weight, divided into 4 doses. In an acute crisis, the dose is 300 mg/kg of body weight, administered intravenously, divided into 4 doses.
- Elderly: Dose adjustment is recommended for elderly patients with impaired renal function. For long-term treatment in the elderly, creatinine clearance should be regularly assessed to adjust the dose as needed.
- Renal Impairment: The daily dose is calculated individually based on renal function.
- Adults:
Contraindications
- Hypersensitivity to piracetam, other pyrrolidone derivatives, or any component of the medication.
- Patients with severe renal impairment (creatinine clearance less than 20 ml/minute).
- Patients with Huntington’s Chorea.
- Cerebral hemorrhage.
Storage & Quality
- Storage: Store in a cool, dry place at a temperature below 30°C, away from light.
- Shelf Life: 36 months from the manufacturing date.
- Quality Standard: Manufacturer’s Standard.
